Matlacha Isles Real Estate

Matlacha Isles is a charming waterfront community located in Lee County, Florida. Situated in the picturesque town of Matlacha, this development offers residents a unique blend of tranquility and convenience. The area is known for its stunning water views, lush tropical landscaping, and a laid-back island atmosphere.

Residents of Matlacha Isles enjoy easy access to a variety of outdoor activities, including boating, fishing, and kayaking. The community is also close to local shops, restaurants, and art galleries, providing plenty of opportunities for entertainment and relaxation.

Homes in Matlacha Isles range from cozy waterfront cottages to spacious modern residences, offering something for everyone. Whether you're looking for a vacation home or a permanent residence, Matlacha Isles has a lot to offer.

If you're searching for a waterfront paradise in Southwest Florida, Matlacha Isles in Lee County is definitely worth considering. Experience the beauty and serenity of waterfront living in this unique and vibrant community.

Newest Listings in Matlacha Isles

12065 Boat Shell Drive, Matlacha Isles image

12065 Boat Shell Drive, Matlacha Isles $500,000

AMAZING PRICE for this beautifully remodeled 3-bedroom, 2-bathroom home located in the desirable Matlacha Isles community. This property features a spacious gross living ...

3 Beds
2 Baths
2026036052 MLS

12100 Moon Shell Drive, Matlacha Isles image

12100 Moon Shell Drive, Matlacha Isles $450,000

Build your dream home in beautiful Matlacha Isles! This waterfront homesite offers Direct Gulf access and an incredible opportunity to enjoy the Southwest Florida boating...

2026033797 MLS

12088 Boat Shell Drive, Matlacha Isles image

12088 Boat Shell Drive, Matlacha Isles $849,000 ▼

Completely renovated and sold fully turnkey, this exceptional waterfront pool home in Matlacha Isles offers the perfect blend of luxury, investment potential, and the ult...

3 Beds
2 Baths
2026033137 MLS

12213 Star Shell Drive, Matlacha Isles image

12213 Star Shell Drive, Matlacha Isles $949,000 ▼

Waterfront Paradise in Matlacha Isles – Sailboat Access, Pool/Hot tub & Dual Boat Lifts Experience the ultimate Southwest Florida waterfront lifestyle in this beautifull...

3 Beds
3 Baths
2026025179 MLS

12279 Matlacha Boulevard, Matlacha Isles image

12279 Matlacha Boulevard, Matlacha Isles $549,900

Old Florida charm meets waterfront living in the heart of Matlacha Isles. Situated on a rare double buildable lot with wide intersecting canal views and direct Gulf acces...

2 Beds
2 Baths
2026022481 MLS

12262 Moon Shell Drive, Matlacha Isles image

12262 Moon Shell Drive, Matlacha Isles $599,500

RARE oversized waterfront opportunity in highly sought-after Matlacha Isles offering the potential for TWO buildable homesites on an expansive 4-lot property currently co...

2026021251 MLS

12068 Matlacha Boulevard, Matlacha Isles image

12068 Matlacha Boulevard, Matlacha Isles $375,000 ▼

MAKE OFFER! ALREADY PRICED A LOT VALUE!!! Your Fishing Hangout! Establish residency now for lower Homestead taxes in this basic Gulf Access single family home, should vot...

2 Beds
2 Baths
2026015635 MLS

12304 Boat Shell Drive, Matlacha Isles image

12304 Boat Shell Drive, Matlacha Isles $825,000 ▼

HOME NEVER FLOODED! LOW FLOOD INSURANCE POLICY IS TRANSFERABLE! TURNKEY Gulf-access waterfront living awaits in this beautifully furnished 3-bedroom, 3-bath pool home, wh...

3 Beds
3 Baths
2025020052 MLS